| Decarbonylative Approach to the Synthesis of Enamides from Amino Acids: Stereoselective Synthesis of the (Z)-Aminovinyl-d-Cysteine Unit of Mersacidin. | |
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MedLine Citation:
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PMID: 22296268 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The Pd- and Ni-promoted decarbonylation of amino acid thioesters proceeds smoothly to yield enamides. The synthesis of the (S)-(Z)-AviMeCys subunit of mersacidin, an MRSA-active lantibiotic, via this approach, is described. |
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Authors:
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Pablo García-Reynaga; Angela K Carrillo; Michael S Vannieuwenhze |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-1 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47505, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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