Document Detail

Decalcification of root canal dentine by citric acid, EDTA and sodium citrate.
MedLine Citation:
PMID:  15186242     Owner:  NLM     Status:  MEDLINE    
AIM: To measure the demineralization capability of 1 and 10% citric acid, 10% sodium citrate and 17% EDTA during immersions of 5, 10 and 15 min on root canal dentine.
METHODOLOGY: Crowns were sectioned from eight maxillary canines. The cementum was removed from the cervical third of the roots to expose the dentine. Canals were prepared using a handpiece-mounted Largo Peeso reamer. A 3-mm thick cross-sectional slice was obtained from the cervical third of each root. Each slice was sectioned into four equal parts. These specimens were assigned to one of four groups (n = 8) for the application of 1% citric acid, 10% citric acid, 10% sodium citrate or 17% EDTA. Each specimen underwent three successive 5-min immersions in each solution at room temperature. The solutions were not renewed between immersions. Two millimetres of solution were collected from the extracts and lanthanum oxide was added for the calcium reading by spectrophotometry. To compare the amounts of calcium removed by each solution, the Friedman test was used for the global comparison and the Wilcoxon test for paired comparisons. Differences between groups were evaluated using the Kruskal-Wallis test for the global comparison and Mann-Whitney test for paired comparisons.
RESULTS: Overall, 1 and 10% citric acid were more effective than EDTA or sodium citrate at the three immersion times (P < 0.001); 10% citric acid was more effective than 1% citric acid (P < 0.001). EDTA and 1 and 10% citric acid showed decreasing effectiveness with time, and the decrease was significant for citric acid at both concentrations (P < 0.001). Although sodium citrate removed little calcium during the three time periods, the small increase recorded was significant (P < 0.01).
CONCLUSIONS: Citric acid at 10% was the most effective decalcifying agent, followed by 1% citric acid, 17% EDTA and 10% sodium citrate.
L F Machado-Silveiro; S González-López; M P González-Rodríguez
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International endodontic journal     Volume:  37     ISSN:  0143-2885     ISO Abbreviation:  Int Endod J     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-09     Completed Date:  2004-07-12     Revised Date:  2013-04-04    
Medline Journal Info:
Nlm Unique ID:  8004996     Medline TA:  Int Endod J     Country:  England    
Other Details:
Languages:  eng     Pagination:  365-9     Citation Subset:  D    
Department of Endodontics, School of Dentistry, University of Pelotas, Pelotas, Brazil.
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MeSH Terms
Calcium / analysis
Chelating Agents / pharmacology*
Citrates / pharmacology
Citric Acid / pharmacology
Decalcification Technique*
Dentin / drug effects*
Edetic Acid / pharmacology
Root Canal Preparation / methods*
Smear Layer*
Statistics, Nonparametric
Reg. No./Substance:
0/Chelating Agents; 0/Citrates; 1Q73Q2JULR/sodium citrate; 60-00-4/Edetic Acid; 7440-70-2/Calcium; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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