| Death due to blood transfusion-induced anaphylactic shock: A case report. | |
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MedLine Citation:
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PMID: 20303818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In medical practice, many clinical accidents due to blood transfusion reactions have been reported, among which, nonhemolytic transfusion reactions (NHTRs) have been mainly reported in recent years. NHTRs induce reactions such as anaphylactic shock and transfusion-related acute lung injury (TRALI); however, few forensic autopsy case reports with blood transfusion reactions including anaphylactic shock have been published. A marker for anaphylactic shock is serum tryptase, which indicates systematic mast cell activation in living patients. In forensic medicine, serum tryptase has been used in the postmortem diagnosis of anaphylactic shock. In this autopsy case report, the blood tryptase level was elevated to 49.0 ng/mL (reference standard level <13.5 ng/mL). When considered comprehensively with autopsy findings and blood typing, we concluded that this patient was suspected to have suffered from anaphylactic shock as a result of blood transfusion. |
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Authors:
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Akina Nara; Toshihiko Aki; Takeshi Funakoshi; Kyoko Uchida; Haruka Nakayama; Koichi Uemura |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-03-19 |
Journal Detail:
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Title: Legal medicine (Tokyo, Japan) Volume: 12 ISSN: 1873-4162 ISO Abbreviation: Leg Med (Tokyo) Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100889186 Medline TA: Leg Med (Tokyo) Country: Ireland |
Other Details:
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Languages: eng Pagination: 148-50 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Section of Forensic Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anaphylaxis / diagnosis*, etiology* Anemia / therapy Blood Grouping and Crossmatching Blood Transfusion / adverse effects* Forensic Pathology Humans Male Tryptases / blood |
| Chemical | |
Reg. No./Substance:
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EC 3.4.21.59/Tryptases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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