Document Detail

Death by midgut infarction: clinical lessons from 88 post-mortems in Auckland, New Zealand.
MedLine Citation:
PMID:  19183377     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mortality rates from acute arterial mesenteric ischaemia remain high. Early diagnosis is of prognostic importance; however, early features are often non-specific, necessitating a high index of suspicion and knowledge of the at-risk patient. This study reviewed three decades of fatal cases in Auckland, New Zealand, to identify risk factors and associated pathologies that might help guide early diagnosis. Diagnostic delay was also evaluated. METHODS: Cases were identified through a pathology database maintained from 1977 to 2006. Autopsy reports were assessed together with available clinical detail. RESULTS: Eighty-eight cases were recovered. Mean age was 75.4 years, with women predominating (57%). Thromboembolic occlusion was the leading cause, followed by thrombotic occlusion. Embolic sources included atrial disease, aortic disease and myocardial infarction. Patients routinely showed extensive comorbidities, especially cardiovascular. Pain was the most constant presenting symptom, but features were often subtle and clinicians frequently misdiagnosed more minor ailments. Of operated patients, 36% received operations within 6 h of admission, 33% within 24 h, 17% at between 1 and 2 days, and the remainder between 2 and 12 days. CONCLUSION: Knowledge of risk factors defined here is important to guide early diagnosis of mesenteric ischaemia. Diagnostic delay is again shown to be significant and case experience gathered in this series may improve doctors' discernment when meeting this condition.
Gregory O'Grady; Shanu Ghambir; Timothy D Koelmeyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ANZ journal of surgery     Volume:  79     ISSN:  1445-2197     ISO Abbreviation:  ANZ J Surg     Publication Date:    2009 Jan-Feb
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-05-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101086634     Medline TA:  ANZ J Surg     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  38-41     Citation Subset:  IM    
Department of Forensic Pathology, University of Auckland, Auckland, New Zealand.
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MeSH Terms
Aged, 80 and over
Mesenteric Arteries*
Mesenteric Vascular Occlusion / diagnosis*,  etiology,  mortality,  surgery
Middle Aged
New Zealand / epidemiology
Retrospective Studies
Risk Factors
Splanchnic Circulation*
Thromboembolism / complications
Thrombosis / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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