Document Detail


Dealing with baseline differences: two principles and two dilemmas.
MedLine Citation:
PMID:  9987061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two principles are presented that describe directional confounds associated with baseline differences: Principle 1: Change scores are confounded with baseline whenever data are skewed. Principle 2: When baseline differences are real, ANCOVA has a directional bias that magnifies differences in one direction and masks those in the other direction. Both principles involve a directional bias that is related to the direction of baseline difference and the direction of the hypothesized difference in change. Ethical dilemmas arise if decisions (whether or not to transform, whether or not to use ANCOVA) are chosen in order to maximize power by capitalizing on the directional bias and Type 1 error.
Authors:
J Jamieson
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of psychophysiology : official journal of the International Organization of Psychophysiology     Volume:  31     ISSN:  0167-8760     ISO Abbreviation:  Int J Psychophysiol     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-05-05     Completed Date:  1999-05-05     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  8406214     Medline TA:  Int J Psychophysiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  155-61     Citation Subset:  IM    
Affiliation:
Department of Psychology, Lakehead University, Thunder Bay, ON, Canada. john.jamieson@lakeheadu.ca
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance*
Confounding Factors (Epidemiology)*
Data Interpretation, Statistical*
Decision Making
Ethics, Professional
Longitudinal Studies*
Psychophysiology / methods*,  standards
Research Design / standards

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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