Document Detail

Deafness due to haemorrhagic labyrinthitis and a review of relapses in Streptococcus suis meningitis.
MedLine Citation:
PMID:  20358139     Owner:  NLM     Status:  MEDLINE    
Deafness is a common and often permanent neurological sequel of Streptococcus (S.) suis meningitis. Suppurative labyrinthitis, rather than direct auditory nerve infection, has been found to be the site responsible for deafness. Neuroimaging is important to localise the site involved in hearing loss and to assess the feasibility of a cochlear implantation. S. suis is very sensitive to penicillin. Although a relapse of S. suis meningitis is uncommon, it can occur despite an adequate duration of appropriate antibiotic therapy. We describe a patient with S. suis meningitis, who developed permanent deafness from haemorrhagic labyrinthitis, as shown on magnetic resonance imaging. She suffered a relapse despite a seven-week course of intravenous antibiotics. A review on six cases of relapse reported in the literature shows that relapses occurred despite two to four weeks of antibiotics being administered to the patients. The clinical implications and treatment of relapse are discussed.
J H Tan; B I Yeh; C S R Seet
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Singapore medical journal     Volume:  51     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-04-01     Completed Date:  2010-07-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e30-3     Citation Subset:  IM    
Division of Neurology, Department of Medicine, National University Hospital, Singapore.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Ceftriaxone / therapeutic use
Cochlea / physiopathology
Cochlear Implants
Hearing Loss / etiology*,  physiopathology,  therapy
Hemorrhage / complications*
Labyrinthitis / complications*
Magnetic Resonance Imaging
Meningitis, Bacterial / complications*
Streptococcal Infections / complications*,  drug therapy
Streptococcus suis*
Reg. No./Substance:
0/Anti-Bacterial Agents; 73384-59-5/Ceftriaxone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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