Document Detail


Deafferentation-disconnection neglect induced by posterior cerebral artery infarction.
MedLine Citation:
PMID:  16401846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate patients with posterior cerebral artery (PCA) infarctions to learn whether hemispatial neglect is more frequent and severe after right than left PCA infarction; whether visual field defects (VFDs) influence the presence or severity of hemispatial neglect; and the anatomic loci of lesions that are associated with hemispatial neglect. METHODS: The authors recruited 45 patients with PCA infarction that involved only the occipital lobe or the occipital lobe plus other areas served by the PCA. All subjects received seven neglect tests within 2 months after onset. RESULTS: Overall, the frequency of hemispatial neglect was 42.2%. The frequency did not significantly differ between the right (48.0%) and left (35.0%) PCA groups, but the severity of hemispatial neglect was significantly greater in the right group. VFD alone did not influence the frequency or severity of neglect after controlling other variables. Isolated occipital lesions were rarely associated with hemispatial neglect, and it was only the occipital plus splenial lesion that significantly influenced the frequency and severity of neglect. CONCLUSIONS: This study suggests that after excluding such confounding factors as aphasia or hemiplegia, neglect frequency does not differ between the right and left posterior cerebral artery (PCA) groups, but the severity of neglect is greater after right PCA infarctions; even in the acute stage of PCA infarction; visual field defect from an isolated occipital lesion does not cause hemispatial neglect; and the injury to both the occipital lobe and the splenium of the corpus callosum is important for producing hemispatial neglect with PCA infarction.
Authors:
K C Park; B H Lee; E J Kim; M H Shin; K M Choi; S S Yoon; S U Kwon; C S Chung; K H Lee; K M Heilman; D L Na
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurology     Volume:  66     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-10     Completed Date:  2006-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  56-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, Kyung Hee University, School of Medicine, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Brain Infarction / diagnosis*,  physiopathology
Cerebral Infarction / diagnosis,  physiopathology
Corpus Callosum / blood supply,  pathology,  physiopathology
Female
Functional Laterality / physiology*
Hemianopsia / diagnosis,  etiology,  physiopathology
Humans
Male
Middle Aged
Occipital Lobe / blood supply,  pathology*,  physiopathology*
Perceptual Disorders / diagnosis*,  etiology,  physiopathology
Posterior Cerebral Artery / pathology,  physiopathology*
Predictive Value of Tests
Space Perception / physiology
Temporal Lobe / blood supply,  pathology,  physiopathology
Thalamus / blood supply,  pathology,  physiopathology
Visual Cortex / blood supply,  pathology,  physiopathology
Visual Fields / physiology
Visual Pathways / blood supply,  pathology,  physiopathology
Visual Perception / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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