Document Detail


De novo development of eosinophilic myocarditis with left ventricular assist device support as bridge to transplant.
MedLine Citation:
PMID:  20868843     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The de novo development of myocarditis during left ventricular assist device support for dilated cardiomyopathy has not been previously described. We report a case of severe eosinophilic myocarditis associated with the use of leukotriene-receptor antagonist montelukast that developed during left ventricular assist device support accompanied by intra-device thrombus formation that was hemodynamically tolerated and subsequently discovered in the explanted heart. There may be no visible change in cardiac function as assessed by echocardiography, but the diagnosis should be entertained with the development of peripheral eosinophilia.
Authors:
Naveen L Pereira; Soon J Park; Richard C Daly; Sudhir S Kushwaha; William D Edwards
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  90     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1345-7     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Affiliation:
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. pereira.naveen@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Acetates / adverse effects*
Cardiomyopathy, Dilated / surgery*
Eosinophilia
Female
Heart Transplantation*
Heart-Assist Devices / adverse effects*
Humans
Leukotriene Antagonists / adverse effects*
Middle Aged
Myocarditis / etiology*,  immunology
Quinolines / adverse effects*
Thrombosis / etiology
Chemical
Reg. No./Substance:
0/Acetates; 0/Leukotriene Antagonists; 0/Quinolines; 158966-92-8/montelukast

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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