Document Detail


'De novo' absence status of late onset: report of 11 cases.
MedLine Citation:
PMID:  1734289     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Absence status (AS) is a heterogenous epileptic syndrome that can occur at any age, usually in a context of prior epilepsy. Eleven cases of AS occurring in middle-aged patients who had no history of epilepsy were retrospectively collected over a 10-year period (10 women and one man; mean age, 58.6 years). Eight patients were receiving high doses of psychotropic drugs. Clinical and EEG presentation was similar to AS occurring in patients with prior epilepsy. Evaluation of precipitating factors revealed that AS coincided with benzodiazepine withdrawal in eight cases. Cofactors included excessive use of other psychotropic drugs, nonpsychotropic treatment, hypocalcemia, hyponatremia, and chronic alcoholism. CT demonstrated mild cerebral atrophy in six cases. There was no recurrence, even without chronic antiepileptic treatment. These data indicate that (1) most cases of "de novo" AS of middle age or late onset result from the addition of various epileptogenic factors; (2) AS can be considered a new and uncommon complication of benzodiazepine withdrawal, and (3) long-term administration of anticonvulsant medication may not be required.
Authors:
P Thomas; A Beaumanoir; P Genton; C Dolisi; M Chatel
Related Documents :
12480789 - Donepezil treatment of vascular dementia.
2817299 - Cerebral venous thrombosis associated with recurrent epilepsy-like attacks.
3800089 - Qrs interval in tricyclic antidepressant overdosage: inaccuracy as a toxicity indicator...
10392199 - Vagus nerve stimulation for medically refractory epilepsy; efficacy and cost-benefit an...
9860069 - Double-blind, placebo-controlled, crossover study of lamotrigine in treatment-resistant...
10932509 - Seizure threshold in electroconvulsive therapy: iii. a long-term study.
18814229 - Feasibility and efficacy of stent redilatation in aortic coarctation.
8341099 - Irritative spontaneous nystagmus following intratympanic gentamicin for menière's dise...
9895389 - Anti-inflammatory drugs and variceal bleeding: a case-control study.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  42     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-03-02     Completed Date:  1992-03-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  104-10     Citation Subset:  AIM; IM    
Affiliation:
Service de Neurologie, Hôpital Pasteur, Nice, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Electroencephalography
Epilepsy, Absence / diagnosis,  etiology,  physiopathology*
Female
Humans
Male
Middle Aged
Movement
Prognosis
Psychotropic Drugs / adverse effects
Substance Withdrawal Syndrome / physiopathology
Chemical
Reg. No./Substance:
0/Psychotropic Drugs
Comments/Corrections
Comment In:
Neurology. 1993 Feb;43(2):452-3   [PMID:  8437725 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical and EEG features of status epilepticus in comatose patients.
Next Document:  Prevention of stroke with ticlopidine: who benefits most? TASS Baseline and Angiographic Data Subgro...