| Daytime and nighttime differences in patterns of performance of primary angioplasty in the treatment of patients with acute myocardial infarction. Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) Study Group. | |
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MedLine Citation:
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PMID: 10577442 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Concern exists regarding the results of primary angioplasty for acute myocardial infarction when the procedure is performed during night hours. METHODS AND RESULTS: Between June 1994 and January 1997, 491 patients with acute myocardial infarction who underwent primary angioplasty procedures were consecutive registered in the Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) study. Three hundred seventy-eight patients (77%) were treated during the day and 113 (23%) at night. Baseline characteristics showed no major differences between the 2 groups. Prehospital delay time was 60 minutes shorter during the night (median value 180 minutes for day, 120 minutes for night, P =.005), and in-hospital time to treatment was 9 minutes longer (median value 85 minutes day, 94 minutes night, P =.037). Patients treated during the night more often received angiotensin-converting enzyme blockers (61.4% day, 76.1% night, P =.004) and the so-called optimal adjunctive therapy (54% day, 64.6% night, P =.045). There were no differences concerning clinical events between the 2 groups. Hospital mortality was 8.7% during the day and 5.3% during the night (univariate analysis P =.238; logistic regression P =.653). CONCLUSIONS: In a clinical setting, primary angioplasty for acute myocardial infarction can be performed safely during the night with a clinically insignificant prolongation of in-hospital time to reperfusion compared with practice during the day. |
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Authors:
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R Zahn; R Schiele; K Seidl; S Schuster; K E Hauptmann; T Voigtländer; M Gottwik; G Berg; T Kunz; H G Glunz; P Limbourg; J Senges |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American heart journal Volume: 138 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1999 Dec |
Date Detail:
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Created Date: 2000-01-18 Completed Date: 2000-01-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1111-7 Citation Subset: AIM; IM |
Affiliation:
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Herzzentrum Ludwigshafen, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty / statistics & numerical data* Female Humans Male Middle Aged Myocardial Infarction / surgery* Prospective Studies Regression Analysis Time Factors |
| Comments/Corrections | |
Comment In:
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Am Heart J. 1999 Dec;138(6 Pt 1):1012-3
[PMID:
10577427
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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