| Day-to-day variability in acid reflux patterns using the BRAVO pH monitoring system. | |
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MedLine Citation:
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PMID: 16340628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & GOALS: The wireless pH monitoring system such as the BRAVO pH system is a significant advancement in the evaluation of patients with gastroesophageal reflux because of its potentially better tolerability and the ability to record data over a 48-hour period. The aim of our study was to evaluate safety, performance, tolerability, and day-to-day variability in acid reflux patterns using the BRAVO pH system. METHODS: A total of 90 consecutive patients (48 men and 42 women) with persistent reflux symptoms underwent BRAVO pH capsule placement from October 2002 to August 2003 at a tertiary care hospital. The BRAVO pH capsule was deployed 6 cm proximal to the squamocolumnar junction under endoscopic guidance. The pH recordings over 48 hours were obtained after uploading data to a computer from the pager-like device that recorded pH signals from the BRAVO pH capsule. RESULTS: Successful pH data over 48 hours was obtained in 90% of patients. Nearly two thirds of patients experienced a variety of symptoms ranging from a foreign body sensation to chest discomfort or pain. Four patients had severe chest pain, 3 of whom required endoscopic removal of the BRAVO pH capsule. In 74.4% of patients, number of reflux events as well as time (%) pH<4 correlated from the first 24-hour period to the second 24-hour period. However, in 28% of patients, no predictable pattern of (%) time pH<4 in the supine position was reproduced from one 24-hour period to the next 24-hour period. CONCLUSIONS: The BRAVO pH system appears a safe and effective method of recording esophageal acid exposure. It is an acceptable alternative for patients who are unwilling or unable to tolerate nasopharyngeal catheter-based pH studies, and it has a potential advantage of the 2-day recording period. |
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Authors:
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Sushil K Ahlawat; David J Novak; Dionne C Williams; Kathleen A Maher; Franca Barton; Stanley B Benjamin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical gastroenterology Volume: 40 ISSN: 0192-0790 ISO Abbreviation: J. Clin. Gastroenterol. Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2005-12-12 Completed Date: 2006-03-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7910017 Medline TA: J Clin Gastroenterol Country: United States |
Other Details:
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Languages: eng Pagination: 20-4 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, Department of Medicine, Georgetown University Hospital, Washington, DC, USA. sushilka@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Capsules Esophageal pH Monitoring / instrumentation* Female Gastroesophageal Reflux / diagnosis* Humans Male Middle Aged Monitoring, Ambulatory / instrumentation* Patient Satisfaction Regression Analysis |
| Chemical | |
Reg. No./Substance:
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0/Capsules |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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