Document Detail

Day 5 expanded blastocysts transferred on same day have comparable outcome to those left for more extended culture and transferred on day 6.
MedLine Citation:
PMID:  22847372     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the outcome of blastocysts showing expansion on day 5 and transferred on day 5 or 6, in comparison with those unexpanded and transferred on day 6.
STUDY DESIGN: Prospective cohort of 221 women prepared for BET classified into three groups according to timing of blastocyst expansion and day of embryo transfer. Group I; with expanded blastocysts on day 5 having day 5 transfer, group II; with expanded blastocysts on day 5 having day 6 transfer and group III ; with delayed expansion undergoing day 6 BET.
RESULTS: Implantation rates, pregnancy rates, ongoing pregnancy rates, and live birth rates in the first 2 groups were almost double the rates in the third group. The figures for implantation rates were 40 % in the first two groups vs. 19 % in the third group (P < 0.05). Pregnancy rates were 60.9 % and 64 % vs. 31.8 % (P < 0.05) and ongoing pregnancy/ live-birth rates were 52.3 % & 56 % vs. 27.3 %.
CONCLUSION: The current study reports better implantation and pregnancy rates with earlier expanding blastocysts regardless of the time of transfer.
Eman Elgindy; Mervat Sheikh-El-Arab Elsedeek
Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2012-07-31
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  29     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-08     Completed Date:  2013-05-03     Revised Date:  2013-10-10    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1111-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Zagazig University School of Medicine, Zagazig, Egypt.
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MeSH Terms
Blastocyst / physiology*
Cohort Studies
Embryo Culture Techniques / methods*
Embryo Implantation
Embryo Transfer / methods*
Live Birth
Pregnancy Rate
Prospective Studies
Sperm Injections, Intracytoplasmic*
Time Factors
Treatment Outcome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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