Document Detail

Day 4 versus day 3 embryo transfer: a prospective study of clinical outcomes.
MedLine Citation:
PMID:  17517409     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the clinical outcomes after day 4 or day 3 embryo transfers in controlled ovarian hyperstimulation-IVF/intracytoplasmic sperm injection (ICSI) cycles. DESIGN: Prospective randomized study. SETTING: Center for Human Reproduction, 'Genesis Athens' Clinic (private gynecological and surgical clinic), Athens, Greece. PATIENT(S): Three hundred fifty women with primary infertility and indication for IVF/ICSI treatment. Patients were randomly allocated to day 4 or day 3 embryo transfer. INTERVENTION(S): Controlled ovarian hyperstimulation, oocyte retrieval, IVF/ICSI, embryo transfer. MAIN OUTCOME MEASURE(S): Implantation rate; clinical, ongoing, and multiple pregnancy rates. RESULT(S): A trend toward higher clinical and ongoing pregnancy rates was noted after day 4 embryo transfers. Implantation and multiple pregnancy rates were comparable after day 4 or day 3 embryo transfers. CONCLUSION(S): The transfer of day 4 embryos in IVF/ICSI cycles may result in favorable implantation and pregnancy rates which are at least comparable to those after the transfer of day 3 embryos.
Konstantinos Pantos; Evangelos Makrakis; Margaret Chronopoulou; Maria Biba; Anastasios Perdikaris; Alex Dafereras
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2007-05-22
Journal Detail:
Title:  Fertility and sterility     Volume:  89     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-11     Completed Date:  2008-03-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  573-7     Citation Subset:  IM    
Center for Human Reproduction, Genesis Athens Clinic, Athens, Greece.
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MeSH Terms
Embryo Culture Techniques
Embryo Implantation
Embryo Transfer*
Fertilization in Vitro*
Infertility / therapy*
Ovulation Induction*
Pregnancy Rate
Prospective Studies
Sperm Injections, Intracytoplasmic*
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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