| Dauricine can inhibit the activity of proliferation of urinary tract tumor cells. | |
| | |
MedLine Citation:
|
PMID: 23199717 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: To explore the anti-tumor effects of asiatic moonseed rhizome extraction-dauricine on bladder cancer EJ cell strain, prostate cancer PC-3Mcell strain and primary cell culture system. METHODS: The main effective component-phenolic alkaloids ofMenispermum dauricum was extracted and separated from asiatic moonseed rhizome by chemical method. MTT method was used to detect dauricine anti-tumor effect. RESULTS: Dauricine had an obvious proliferation inhibition effect on the main tumor cells in urinary system. The minimum drug sensitivity concentration was between 3.81-5.15 μg/mL, and the inhibition ratio increased with the increase of concentration. CONCLUSIONS: Dauricine, the main effective component extracted from asiatic moonseed rhizome, had a good inhibition effect on tumor cells in urinary system. At the same time, Dauricine has certain inhibition effects on the primary cultured tumor cell. |
| | |
Authors:
|
Jun Wang; Yuan Li; Xiong-Bing Zu; Min-Feng Chen; Lin Qi |
Related Documents
:
|
16452217 - Growth properties of colonic tumor cells are a function of the intrinsic mitochondrial ... 15350527 - A paradoxical pro-apoptotic effect of thrombin on smooth muscle cells. 10656767 - Adult apaf-1-deficient mice exhibit male infertility. 8616847 - Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondri... 7806587 - Analyzing the metastatic phenotype. 16521697 - Cytotoxicity of alpha-tocopheryl succinate, malonate and oxalate in normal and cancer c... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Asian Pacific journal of tropical medicine Volume: 5 ISSN: 1995-7645 ISO Abbreviation: Asian Pac J Trop Med Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-12-03 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101533720 Medline TA: Asian Pac J Trop Med Country: Singapore |
Other Details:
|
Languages: eng Pagination: 973-6 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 Hainan Medical College. Published by Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Urology, Xiangya Hospital, Central South University, Changsha Hunan Province, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of Kupffer cells on immune tolerance in liver transplantation.
Next Document: Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba ...