Document Detail

Dark-adapted oscillatory potentials in preterm infants with and without retinopathy of prematurity.
MedLine Citation:
PMID:  23334439     Owner:  NLM     Status:  Publisher    
PURPOSE: To describe the appearance and maturation of dark-adapted oscillatory potentials (OPs) in electroretinograms (ERGs) recorded from preterm infants, and to determine any effect of retinopathy of prematurity (ROP). METHODS: Dark-adapted ERGs were recorded in conjunction with screening for ROP and at outpatient follow-up, using a flash luminance of 11.3 scot cd s m(-2) (4.06 phot cd s m(-2)). Eligible infants were born before 31 weeks' gestation and/or weighed ≤1,250 grams at birth. RESULTS: Presence or absence of OPs was established for 68 ERG recordings from 38 infants at maturities ranging from 30 weeks' postmenstrual age (PMA) to 28 weeks' post-term corrected age. 20 infants did not develop ROP, eight developed stage 1, one stage 2 and one stage 3 disease which regressed spontaneously. Eight infants received treatment for threshold ROP. OPs were present in 50 % of infants at 36 weeks' PMA and in all by 50 weeks' PMA. The earliest appearance of OPs was at 30+5 weeks' PMA. Individual OP amplitudes increased and peak time of individual OPs decreased with increasing maturity. For infants with threshold ROP summed OP amplitudes tended to be smaller prior to treatment (6.5 vs 9.9μV, P = 0.09) and were significantly smaller by 50 weeks' PMA (14 vs 30μV, P = 0.007). OP1 was less likely to be present in infants who developed stage 3 or worse ROP (P = 0.000). CONCLUSIONS: Dark-adapted OPs are recordable in some preterm infants from 30 weeks' PMA. Relative suppression of early OPs is a potential marker for developing ROP.
Helen Mactier; Michael S Bradnam; Ruth Hamilton
Related Documents :
10456239 - Feeding, medical factors, and developmental outcome in premature infants.
19447409 - Paco2 and neurodevelopment in extremely low birth weight infants.
7099879 - Infants' mental and motor development: effects of home environment, maternal attitudes,...
6354629 - Developmental lags in preterm infants from one to three years of age.
23013909 - Neonatal and infant pulmonary thromboembolism: a literature review.
24397409 - Correlation analysis between echocardiographic flow pattern and n-terminal-pro-brain na...
20063179 - Measuring birth weight in developing countries: does the method of reporting in retrosp...
8727839 - Feeding interactions in infants with very low birth weight and bronchopulmonary dysplasia.
15244229 - The role of matrix metalloproteinases -9 and -2 in development of neonatal chronic lung...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-20
Journal Detail:
Title:  Documenta ophthalmologica. Advances in ophthalmology     Volume:  -     ISSN:  1573-2622     ISO Abbreviation:  Doc Ophthalmol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370667     Medline TA:  Doc Ophthalmol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Neonatal Unit, Princess Royal Maternity, 8-16, Alexandra Parade, Glasgow, G31 2ER, Scotland, UK,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Xerophthalmia and acquired night blindness in a patient with a history of gastrointestinal neoplasia...
Next Document:  Chemical and topological short-range orders in the ternary Ni-Zr-Al metallic glasses studied by Mont...