| Dapsone resistant leprosy, the western Kenya experience. | |
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MedLine Citation:
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PMID: 4035777 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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41 patients out of 804 registered lepromatous (LL) and borderline lepromatous (BL) patients were studied for possible dapsone resistance by series of biopsy specimens, skin smears and clinical examination. These patients were drawn from a pool of 4384 registered leprosy patients in the west Kenya Leprosy Control Project area. Six out of fourty one cases (14.6%) were confirmed as dapsone resistant by series of biopsy specimens taken when patients were on supervised dapsone therapy; 11 patients (26.8%) were suspected to be resistant and 24 patients (58.6%) responded well to dapsone therapy. All the confirmed cases were lepromatous leprosy cases. We therefore found that there is dapsone resistance here with a maximal prevalence rate of 7 per 1000 in all lepromatous cases and 14.6% in clinically suspicious cases. |
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Authors:
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P A Orege; D M Owili |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Tropical and geographical medicine Volume: 37 ISSN: 0041-3232 ISO Abbreviation: Trop Geogr Med Publication Date: 1985 Jun |
Date Detail:
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Created Date: 1985-09-30 Completed Date: 1985-09-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376231 Medline TA: Trop Geogr Med Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 139-42 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dapsone
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therapeutic use* Drug Resistance, Microbial Humans Kenya Leprosy / drug therapy* |
| Chemical | |
Reg. No./Substance:
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80-08-0/Dapsone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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