Document Detail

Daily variation of blood pressure in patients with Cushing's syndrome.
MedLine Citation:
PMID:  3672505     Owner:  NLM     Status:  MEDLINE    
The circadian rhythm of blood pressure (BP) was compared between patients with Cushing's syndrome and those with essential hypertension. In patients with essential hypertension, clear nocturnal falls in systolic and diastolic BP and heart rate (HR) were observed, and there was a positive correlation between HR and systolic or diastolic BP. On the other hand, in patients with Cushing's syndrome, there was no nocturnal fall in BP and instead a rise in some cases. In all cases with Cushing's syndrome there was a nocturnal fall in HR, and consequently no significant correlation between HR and BP in these patients. The present results imply that the normal circadian rhythm of blood pressure may be regulated at least in part by the hypothalamo-pituitary-adrenal system.
Y Imai; K Abe; S Sasaki; N Minami; M Nihei; M Munakata; H Sekino; K Yoshinaga
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  153     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-11-25     Completed Date:  1987-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  67-74     Citation Subset:  IM    
Second Department of Internal Medicine, Tohoku University School of Medicine, Sendai.
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MeSH Terms
Blood Pressure*
Circadian Rhythm
Cushing Syndrome / physiopathology*
Heart Rate
Hypertension / physiopathology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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