Document Detail


Daidzein and genistein content of fruits and nuts.
MedLine Citation:
PMID:  11002128     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Dietary phytoestrogens such as the isoflavones daidzein and genistein are thought to protect against chronic diseases that are common in Western societies, such as cancer, osteoporosis, and ischemic heart disease. In addition, there are concerns regarding the deleterious effects of hormone-like compounds, especially with respect to the development of infants. However, there is little information regarding the phytoestrogen content of foods, and therefore epidemiologic investigations of phytoestrogens are limited. As part of a study quantifying the consumption of phytoestrogens, the objective of this work was to assess the daidzein and genistein content of fruits and nuts commonly eaten in Europe. Eighty different fruits and nuts were sampled, prepared for eating, and freeze-dried. Daidzein and genistein were extracted from the dried foods, and the two isoflavones were quantified after hydrolytic removal of any conjugated carbohydrate. Completeness of extraction and any procedural losses of the isoflavones were accounted for using synthetic daidzin (7-O-glucosyl-4'-hydroxyisoflavone) and genistin (7-O-glucosyl-4'5-dihydroxyisoflavone) as internal standards. Of the 80 foods assayed, 43 contained no detectable daidzein or genistein, at a limit of quantification of 1 microg/kg dry weight of food. Nine foods contained more than 100 microg of the two isoflavones combined per kilogram wet weight, and 28 contained less than this amount. Currants and raisins were the richest sources of the isoflavones, containing 2,250 microg and 1,840 microg of the two isoflavones combined per kilogram of wet weight of food. Although fruits and nuts are not as rich in isoflavone phytoestrogens as are soy and other legumes, this is the first documentation of levels of daidzein and genistein occurring in these foods.
Authors:
J Liggins; L J Bluck; S Runswick; C Atkinson; W A Coward; S A Bingham
Related Documents :
2305708 - Milk selenium of rural african women: influence of maternal nutrition, parity, and leng...
24643758 - The evaluation of a food allergy and epinephrine autoinjector training program for pers...
18346308 - Food-chain selenium and human health: emphasis on intake.
11599698 - Sporulation of eimeria maxima oocysts in litter with different moisture contents.
2305708 - Milk selenium of rural african women: influence of maternal nutrition, parity, and leng...
25157498 - Overweight adolescents eat what? and when? analysis of consumption patterns to guide di...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of nutritional biochemistry     Volume:  11     ISSN:  0955-2863     ISO Abbreviation:  J. Nutr. Biochem.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2004-06-21     Completed Date:  2005-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010081     Medline TA:  J Nutr Biochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  326-31     Citation Subset:  -    
Affiliation:
Medical Research Council, Dunn Human Nutrition Unit, Cambridge, United Kingdom.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Differential expression of cholesteryl ester transfer protein in the liver and plasma of fasted and ...
Next Document:  Identification of the human beta-casein C-terminal fragments that specifically bind to purified anti...