Document Detail


DNA flow cytometric evaluation of serous and mucinous cystic neoplasms of the pancreas.
MedLine Citation:
PMID:  2039342     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There have been few reports of flow cytometric studies of pancreatic neoplasms, whether endocrine or exocrine. In this report, the DNA content of three mucinous and seven serous cystic tumors of the pancreas was evaluated by flow cytometry on formaldehyde solution-fixed, paraffin-embedded tissue. Two serous cystadenomas were aneuploid, with the remaining five serous and all three mucinous being diploid. All cases had a low S phase (ranging from 0.1% to 3.1%), indicating neoplasms with a low turnover. From these results, it appeared that DNA flow cytometry as an independent factor did not discriminate between the benign pancreatic serous cystadenomas and the more aggressive mucinous cystic neoplasms.
Authors:
P D Unger; P O Danque; A Fuchs; M Kaneko
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  115     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-06-28     Completed Date:  1991-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  563-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cystadenoma / genetics*,  pathology
DNA, Neoplasm / analysis*
Female
Flow Cytometry*
Humans
Male
Middle Aged
Pancreatic Neoplasms / genetics*,  pathology
Chemical
Reg. No./Substance:
0/DNA, Neoplasm

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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