| DNA-based delivery vehicles: pH-controlled disassembly and cargo release. | |
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MedLine Citation:
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PMID: 23143043 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Non-Watson-Crick base pairing provides an in situ approach for actuation of DNA nanostructures through responses to solution conditions. Here we demonstrate this concept by using physiologically-relevant changes in pH to regulate DNA pyramid assembly/disassembly and to control the release of protein cargo. |
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Authors:
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Jung-Won Keum; Harry Bermudez |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-12 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: - ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Chemical Engineering, University of Massachusetts, Amherst, MA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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