| DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy. | |
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MedLine Citation:
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PMID: 23319350 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Lighting the way with DNA: Molecular beacon micelle flares (MBMFs), based on self-assembly of diacyllipid-molecular-beacon conjugates (L-MBs; see figure), have been developed for combined mRNA detection and gene therapy. These MBMFs were shown to inhibit a model gene in vitro and decrease the viability of cancer cells in culture. |
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Authors:
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Tao Chen; Cuichen Sam Wu; Elizabeth Jimenez; Zhi Zhu; Joshua G Dajac; Mingxu You; Da Han; Xiaobing Zhang; Weihong Tan |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-14 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: Angew. Chem. Int. Ed. Engl. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Center for Research at Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, FL 32611-7200 (USA). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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