Document Detail

DMBA and immunosuppression in the Syrian golden hamster.
MedLine Citation:
PMID:  1067318     Owner:  NLM     Status:  MEDLINE    
The immunosuppressive effects of topically applied 9, 10 dimethyl 1, 2 benzanthracene (DMBA) were investigated in the Syrian Golden hamster. Tri-weekly doses of DMBA were administered, with some hamsters receiving both DMBA and X-radiation. DMBA and DMBA-plus-radiation groups demonstrated decreased immune responsiveness relative to their control counterparts. Potential immunosuppressive effects of carcinogen and carcinoma are discussed.
A R Gould
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of dental research     Volume:  55 Spec No     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1976-12-03     Completed Date:  1976-12-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  D98-102     Citation Subset:  D; IM    
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MeSH Terms
Carcinoma / chemically induced,  immunology
Hemagglutination Tests
Immunity / drug effects*,  radiation effects
Immunosuppressive Agents*
Mouth Neoplasms / chemically induced,  immunology
Neoplasms, Experimental / chemically induced,  immunology
Reg. No./Substance:
0/Immunosuppressive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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