| DCCT and EDIC studies in type 1 diabetes: lessons for diabetic neuropathy regarding metabolic memory and natural history. | |
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MedLine Citation:
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PMID: 20464532 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The DCCT/EDIC (Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications) provides a comprehensive characterization of the natural history of diabetic neuropathy in patients with type 1 diabetes and provides insight into the impact of intensive insulin therapy in disease progression. The lessons learned about the natural history of distal symmetrical polyneuropathy and cardiovascular autonomic neuropathy and the impact of glycemic control on neuropathy are discussed in this review. |
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Authors:
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Rodica Pop-Busui; William H Herman; Eva L Feldman; Phillip A Low; Catherine L Martin; Patricia A Cleary; Barbara H Waberski; John M Lachin; James W Albers; |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Current diabetes reports Volume: 10 ISSN: 1539-0829 ISO Abbreviation: Curr. Diab. Rep. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-06-24 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101093791 Medline TA: Curr Diab Rep Country: United States |
Other Details:
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Languages: eng Pagination: 276-82 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. rpbusui@umich.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autonomic Nervous System Diseases
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etiology,
therapy Cardiomyopathies / etiology, therapy Diabetes Mellitus, Type 1 / complications*, drug therapy, metabolism, therapy* Diabetic Neuropathies / etiology*, metabolism Female Humans Hypoglycemic Agents / therapeutic use Insulin / therapeutic use Male Randomized Controlled Trials as Topic* |
| Chemical | |
Reg. No./Substance:
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0/Hypoglycemic Agents; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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