Document Detail

The DASH diet and insulin sensitivity.
MedLine Citation:
PMID:  21058045     Owner:  NLM     Status:  MEDLINE    
Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who are overweight or obese, and physical activity, are effective in the prevention and treatment of hypertension. A healthy lifestyle may also have beneficial effects on metabolic abnormalities, such as insulin resistance, that are associated with high blood pressure. This review examines the independent and combined effects of the DASH diet and weight loss plus exercise on blood pressure and insulin sensitivity, with a focus on recently published results from the ENCORE study. Our data suggest that the DASH eating plan alone lowers blood pressure in overweight individuals with higher than optimal blood pressure, but significant improvements in insulin sensitivity are observed only when the DASH diet is implemented as part of a more comprehensive lifestyle modification program that includes exercise and weight loss.
Alan L Hinderliter; Michael A Babyak; Andrew Sherwood; James A Blumenthal
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  13     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-04     Completed Date:  2011-05-04     Revised Date:  2013-09-16    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  67-73     Citation Subset:  IM    
Department of Medicine, Division of Cardiology, University of North Carolina, Chapel Hill, NC 27599-7075, USA.
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MeSH Terms
Blood Pressure / drug effects,  physiology
Diabetes Mellitus / metabolism*,  pathology
Diet, Sodium-Restricted*
Health Behavior
Hypertension / metabolism*,  pathology
Insulin Resistance*
Life Style
Motor Activity
Nutritional Status
Weight Loss
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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