Document Detail

A DAQ-Device-Based Continuous Wave Near-Infrared Spectroscopy System for Measuring Human Functional Brain Activity.
MedLine Citation:
PMID:  25180044     Owner:  NLM     Status:  In-Data-Review    
In the last two decades, functional near-infrared spectroscopy (fNIRS) is getting more and more popular as a neuroimaging technique. The fNIRS instrument can be used to measure local hemodynamic response, which indirectly reflects the functional neural activities in human brain. In this study, an easily implemented way to establish DAQ-device-based fNIRS system was proposed. Basic instrumentation components (light sources driving, signal conditioning, sensors, and optical fiber) of the fNIRS system were described. The digital in-phase and quadrature demodulation method was applied in LabVIEW software to distinguish light sources from different emitters. The effectiveness of the custom-made system was verified by simultaneous measurement with a commercial instrument ETG-4000 during Valsalva maneuver experiment. The light intensity data acquired from two systems were highly correlated for lower wavelength (Pearson's correlation coefficient r = 0.92, P < 0.01) and higher wavelength (r = 0.84, P < 0.01). Further, another mental arithmetic experiment was implemented to detect neural activation in the prefrontal cortex. For 9 participants, significant cerebral activation was detected in 6 subjects (P < 0.05) for oxyhemoglobin and in 8 subjects (P < 0.01) for deoxyhemoglobin.
Gang Xu; Xiaoli Li; Duan Li; Xiaomin Liu
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Publication Detail:
Type:  Journal Article     Date:  2014-08-10
Journal Detail:
Title:  Computational and mathematical methods in medicine     Volume:  2014     ISSN:  1748-6718     ISO Abbreviation:  Comput Math Methods Med     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101277751     Medline TA:  Comput Math Methods Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107320     Citation Subset:  IM    
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