Document Detail


D21S215 is a (GT)n polymorphic marker close to centromeric alphoid sequences on chromosome 21.
MedLine Citation:
PMID:  1505976     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A plasmid, AWZ1, that contained a dinucleotide (GT)n repeat was identified from a chromosome 21-specific genomic library. When amplified by PCR from human genomic DNA, the repeat length was highly polymorphic between individuals; its location, D21S215, was mapped in the CEPH pedigrees by linkage analysis to the pericentromeric region of chromosome 21. It is the closest polymorphic marker to alphoid sequences on this chromosome.
Authors:
A C Warren; M B Petersen; W Van Hul; M G McInnis; C Van Broeckhoven; T K Cox; A Chakravarti; S E Antonarakis
Related Documents :
10708486 - The expansion of the cag repeat in exon 1 of the human androgen receptor gene is associ...
8776586 - Population screening at the fraxa and fraxe loci: molecular analyses of boys with learn...
9158156 - Estimating y chromosome specific microsatellite mutation frequencies using deep rooting...
20008936 - Fusion of nearby inverted repeats by a replication-based mechanism leads to formation o...
1842476 - Concomitant incidence of fertility chance reducing varicocele and chromosome aberration.
12552086 - Determination of the transcriptome of vibrio cholerae during intraintestinal growth and...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genomics     Volume:  13     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-22     Completed Date:  1992-09-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1365-7     Citation Subset:  IM    
Affiliation:
Center for Medical Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/M95740;  M96652;  S43119;  S43409;  S99543;  S99546;  S99553;  S99558;  S99567;  X61631
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Centromere*
Chromosomes, Human, Pair 21*
Electrophoresis, Polyacrylamide Gel
Female
Genetic Markers*
Genotype
Humans
Male
Mice
Molecular Sequence Data
Oligonucleotides
Plasmids
Polymerase Chain Reaction
Polymorphism, Genetic*
Grant Support
ID/Acronym/Agency:
HD24605/HD/NICHD NIH HHS; HG00373/HG/NHGRI NIH HHS
Chemical
Reg. No./Substance:
0/Genetic Markers; 0/Oligonucleotides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  De novo splice site mutation in the antithrombin III (AT3) gene causing recurrent venous thrombosis:...
Next Document:  A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prade...