| Cytotoxic effect of four root filling materials. | |
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MedLine Citation:
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PMID: 11202896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the cytotoxic effect of four root canal sealers: AH26, AH Plus, Diaket and Apexit. In the experiment two cell lines, human cervical carcinoma (HeLa) cells and mouse skin fibroblasts (L929), were used. Under aseptic conditions, the sealers were prepared according to the manufacturers' directions, and 0.01 mL of each material was placed in a 24-well plate. The sealers were covered with cell suspension. The cytotoxicity was estimated by determining the number of viable cells by a light microscope, as well as the total number of cells 24 h, 48 h and 120 h after the treatment with mentioned materials. The results obtained in this study showed the high cytotoxcity of the new AH Plus root canal sealer, which was shown to be equally or more toxic to the standard AH26 and Diaket materials. Apexit was the least toxic sealer. |
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Authors:
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I Miletić; I Anić; Z Karlović; T Marsan; S Pezelj-Ribarić; M Osmak |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Endodontics & dental traumatology Volume: 16 ISSN: 0109-2502 ISO Abbreviation: Endod Dent Traumatol Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2001-02-02 Completed Date: 2001-03-15 Revised Date: 2012-03-05 |
Medline Journal Info:
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Nlm Unique ID: 8508054 Medline TA: Endod Dent Traumatol Country: Denmark |
Other Details:
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Languages: eng Pagination: 287-90 Citation Subset: D |
Affiliation:
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Department of Dental Pathology, School of Dentistry, University of Zagreb, Zagreb, Croatia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bismuth / toxicity Calcium Hydroxide / toxicity Cell Count Cell Line Cell Size / drug effects Cell Survival / drug effects Drug Combinations Epoxy Resins / toxicity Fibroblasts / drug effects HeLa Cells / drug effects Humans Methenamine / toxicity Mice Polyvinyls / toxicity Root Canal Filling Materials / toxicity* Silver / toxicity Skin / cytology, drug effects Statistics as Topic Time Factors Titanium / toxicity Tumor Cells, Cultured Zinc Oxide / toxicity |
| Chemical | |
Reg. No./Substance:
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0/Apexit; 0/Drug Combinations; 0/Epoxy Resins; 0/Polyvinyls; 0/Root Canal Filling Materials; 0/expoy resin-based root canal sealer; 100-97-0/Methenamine; 1305-62-0/Calcium Hydroxide; 1314-13-2/Zinc Oxide; 55599-25-2/epoxy resin AH-26; 56509-77-4/Diaket; 7440-22-4/Silver; 7440-32-6/Titanium; 7440-69-9/Bismuth |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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