| Cytotoxic constituents of ethyl acetate fraction from Dianthus superbus. | |
| | |
MedLine Citation:
|
PMID: 23351147 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The ethyl acetate fraction (EE-DS) from Dianthus superbus was found to possess the cytotoxic activity against cancer cells in previous study. To investigate cytotoxic constituents, the bioassay-guided isolation of compounds from EE-DS was performed. Two dianthramides (1 and 2), three flavonoids (3-5), two coumarins (6 and 7) and three other compounds (8-10) were obtained. Structures of isolated compounds were identified by spectroscopic analysis. Cytotoxicity of the compounds against HepG2 cells was evaluated. Compound 1 showed the strongest cytotoxicity, compounds 10, 4, 3 and 5 had moderate cytotoxicity. |
| | |
Authors:
|
Chengli Ding; Wu Zhang; Jie Li; Jiachuan Lei; Jianqing Yu |
Related Documents
:
|
22436277 - Degradation of terpenes and terpenoids from mediterranean rangelands by mixed rumen bac... 19483347 - Hepatoprotective constituents from cleome droserifolia. 23390477 - Deferasirox reduces oxidative stress in patients with transfusion dependency. 23600387 - Chalcone-based derivatives as new scaffolds for ha3 adenosine receptor antagonists. 2224887 - De novo synthesis of carbohydrates by stereoselective aldol reaction: l-cladinose. 21699247 - Ring-opening copolymerization of maleic anhydride with epoxides: a chain-growth approac... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-28 |
Journal Detail:
|
Title: Natural product research Volume: - ISSN: 1478-6427 ISO Abbreviation: Nat. Prod. Res. Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101167924 Medline TA: Nat Prod Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
a Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, Wuhan University School of Pharmaceutical Sciences , Wuhan , 430071 , P.R. China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Associations of epicardial fat with coronary calcification, insulin resistance, inflammation, and fi...
Next Document: Standardized comparison of robot-assisted limited and extended pelvic lymphadenectomy for prostate c...