Document Detail


Cytotoxic constituents of ethyl acetate fraction from Dianthus superbus.
MedLine Citation:
PMID:  23351147     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The ethyl acetate fraction (EE-DS) from Dianthus superbus was found to possess the cytotoxic activity against cancer cells in previous study. To investigate cytotoxic constituents, the bioassay-guided isolation of compounds from EE-DS was performed. Two dianthramides (1 and 2), three flavonoids (3-5), two coumarins (6 and 7) and three other compounds (8-10) were obtained. Structures of isolated compounds were identified by spectroscopic analysis. Cytotoxicity of the compounds against HepG2 cells was evaluated. Compound 1 showed the strongest cytotoxicity, compounds 10, 4, 3 and 5 had moderate cytotoxicity.
Authors:
Chengli Ding; Wu Zhang; Jie Li; Jiachuan Lei; Jianqing Yu
Related Documents :
22436277 - Degradation of terpenes and terpenoids from mediterranean rangelands by mixed rumen bac...
19483347 - Hepatoprotective constituents from cleome droserifolia.
24484237 - A new guaianolide sesquiterpene lactone from curcuma leucorrhiza roxb.
23831897 - Renewable biofuel additives from the ozonolysis of lignin.
2224887 - De novo synthesis of carbohydrates by stereoselective aldol reaction: l-cladinose.
21699247 - Ring-opening copolymerization of maleic anhydride with epoxides: a chain-growth approac...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  Natural product research     Volume:  -     ISSN:  1478-6427     ISO Abbreviation:  Nat. Prod. Res.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, Wuhan University School of Pharmaceutical Sciences , Wuhan , 430071 , P.R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Associations of epicardial fat with coronary calcification, insulin resistance, inflammation, and fi...
Next Document:  Standardized comparison of robot-assisted limited and extended pelvic lymphadenectomy for prostate c...