| Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana. | |
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MedLine Citation:
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PMID: 18214815 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive. |
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Authors:
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Jesús G Díaz; Armando J Carmona; Fernando Torres; José Quintana; Francisco Estévez; Werner Herz |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-01-23 |
Journal Detail:
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Title: Planta medica Volume: 74 ISSN: 0032-0943 ISO Abbreviation: Planta Med. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-20 Completed Date: 2008-05-21 Revised Date: 2008-07-30 |
Medline Journal Info:
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Nlm Unique ID: 0066751 Medline TA: Planta Med Country: Germany |
Other Details:
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Languages: eng Pagination: 171-4 Citation Subset: IM |
Affiliation:
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Instituto Universitario de Bio-Orgánica Antonio González, La Laguna, Tenerife, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Division
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drug effects Cell Line, Tumor Cell Survival / drug effects* Flavonoids / pharmacology* Galactosides / pharmacology* Glycosides / pharmacology* HL-60 Cells / drug effects Humans Kaempferols / pharmacology* Methylation Plant Extracts / isolation & purification*, pharmacology* Ranunculaceae / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Flavonoids; 0/Galactosides; 0/Glycosides; 0/Kaempferols; 0/Plant Extracts; 0/trifolin acetate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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