| Cytotoxic Triterpenoid Saponins from Ardisia gigantifolia. | |
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MedLine Citation:
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PMID: 22314414 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Three new triterpenoid saponins, 1- 3, together with two known saponins, 4 and 5, were isolated from the rhizome of ARDISIA GIGANTIFOLIA. Their structures were elucidated by 1D and 2D NMR spectroscopic studies. Saponins 1, 2, 4, and 5 exhibited significant cytotoxicity against four human cancer cell lines, namely, Hela human cervical carcinoma cells, EJ human bladder tumor cells, HepG-2 human hepatoma cells, and BCG human gastric carcinoma cells with IC (50) values in the range of 1.9-4.8 µM. |
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Authors:
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Li-Hua Mu; Ning-Yan Wei; Ping Liu |
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Publication Detail:
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Type: LETTER Date: 2012-2-7 |
Journal Detail:
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Title: Planta medica Volume: - ISSN: 1439-0221 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0066751 Medline TA: Planta Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Department of Clinical Pharmacology, General Hospital of PLA, Beijing, PR China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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