Document Detail


Cytoprotective effect of Panax ginseng on gallic acid-induced toxicity in TM3 mouse Leydig cells.
MedLine Citation:
PMID:  17553632     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide.
Authors:
Wansu H Park; Mun Seog Chang; Woong Mo Yang; Hyunsu Bae; Nam Il Kim; Seong Kyu Park
Publication Detail:
Type:  Journal Article     Date:  2007-05-10
Journal Detail:
Title:  Fitoterapia     Volume:  78     ISSN:  0367-326X     ISO Abbreviation:  Fitoterapia     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-10-30     Completed Date:  2008-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  16930290R     Medline TA:  Fitoterapia     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  577-9     Citation Subset:  IM    
Affiliation:
College of Oriental Medicine, Kyungwon University, Seongnam 461-701, South Korea. hangl98@naver.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Cells, Cultured
Dose-Response Relationship, Drug
Gallic Acid / diagnostic use
Hydrogen Peroxide / metabolism
Leydig Cells / drug effects,  metabolism
Male
Mice
Panax*
Phytotherapy*
Plant Extracts / administration & dosage,  pharmacology*,  therapeutic use
Plant Roots
Protective Agents / administration & dosage,  pharmacology*,  therapeutic use
Chemical
Reg. No./Substance:
0/Plant Extracts; 0/Protective Agents; 149-91-7/Gallic Acid; 7722-84-1/Hydrogen Peroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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