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Cytoprotective, antihyperglycemic and phytochemical properties of Cocos nucifera (L.) inflorescence.
MedLine Citation:
PMID:  23870470     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the cytoprotective and antidiabetic activities as well as phytochemical composition of the immature inflorescence of Cocos nucifera belonging to the Arecaceae Family.
METHODS: The phytochemical screening of inflorescence was done to determine the major constituents present in Cocos nucifera inflorescence. The free radical scavenging potential of inflorescence extracts were evaluated using in vitro radical scavenging assay models.
RESULTS: The phytochemical analyses on inflorescence showed the presence of phenolic compounds, flavonoids, resins and alkaloids. The macronutrient analyses, on the other hand, showed the presence of carbohydrate, proteins and fibers. Administration of the methanol extract of coconut inflorescence to the diabetic rats showed dose dependent reduction in hyperglycemia. The cytoprotective property of coconut inflorescence was evidenced from the acute toxicological evaluation. The levels of serum aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase were significantly decreased in the diabetic rats treated with inflorescence when compared with the diabetic control rats.
CONCLUSION: The results obtained from the present study apparently proved the non-toxic nature and the cytoprotective and antihyperglycemic properties of coconut inflorescence.
Authors:
Rs Renjith; Am Chikku; T Rajamohan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian Pacific journal of tropical medicine     Volume:  6     ISSN:  1995-7645     ISO Abbreviation:  Asian Pac J Trop Med     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-07-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101533720     Medline TA:  Asian Pac J Trop Med     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  804-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Biochemistry, University of Kerala, Thiruvananthapuram-695581, Kerala, India.
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