Document Detail


Cytophotometric studies of cell populations.
MedLine Citation:
PMID:  6163545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Technologic advances in the recording of digitized imagery have made the study of large cell populations by image analytical methods feasible. Computed image information provides quantitative, and novel, information that allows an exact measurement of minute changes in the chromatin distribution of cell nuclei, and the detection of subpopulations of cells or changes in the functional state of the cells. The sensitivity of the detection exceeds that of human observers; the specificity of the measured changes must be the subject of basic cell biologic research.
Authors:
P H Bartels; G B Olson; R Lockart; G L Wied
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cell biophysics     Volume:  2     ISSN:  0163-4992     ISO Abbreviation:  Cell Biophys.     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-06-13     Completed Date:  1981-06-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8002185     Medline TA:  Cell Biophys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  339-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Line
Cell Nucleus / ultrastructure*
Chromatin / analysis*
Computers*
Cytological Techniques*
Humans
Interferons / pharmacology
Lymphocyte Activation
Spectrophotometry
Grant Support
ID/Acronym/Agency:
2RO1 CA-13261-11/CA/NCI NIH HHS; 2RO1 CA-15641/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Chromatin; 9008-11-1/Interferons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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