Document Detail


Cytopathogenicity of Naegleria fowleri in mammalian cell cultures.
MedLine Citation:
PMID:  2622894     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A total of 13 strains of Naegleria fowleri were cytopathogenic for lung, kidney, foreskin, ovary, connective tissue, neuroblastoma, laryngeal carcinoma, and cervical carcinoma mammalian cell lines. The strains of N. fowleri varied considerably in their ability to produce a cytopathic effect (CPE). Likewise, the different mammalian cell lines exhibited varying degrees of susceptability to the cytopathogenicity of the amebae. The African green-monkey kidney (Vero) cell line proved to be useful for assessing the cytopathogenic potential of N. fowleri strains. Although one strain failed to produce CPE in Vero-cell cultures, it did so in the two neuroblastoma cell lines. Other factors affecting the extent of CPE produced were incubation temperature, ameba: mammalian cell ratio, and the length of time during which amebae were maintained in cell culture.
Authors:
D T John; R A John
Related Documents :
19200884 - Cytosolic lc3 ratio as a quantitative index of macroautophagy.
25294904 - Genetic evolution of t-cell resistance in the course of melanoma progression.
2554694 - Microbeads and anchorage-dependent eukaryotic cells: the beginning of a new era in biot...
7730414 - A novel mammalian myosin i from rat with an sh3 domain localizes to con a-inducible, f-...
7577744 - Dna content in colorectal carcinoma: a flow cytometric study of the epithelial fraction.
116194 - Series of 4.5s rnas associated with poly(a)-containing rnas of rodent cells.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Parasitology research     Volume:  76     ISSN:  0932-0113     ISO Abbreviation:  Parasitol. Res.     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-19     Completed Date:  1990-03-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8703571     Medline TA:  Parasitol Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  20-5     Citation Subset:  IM    
Affiliation:
Department of Microbiology/Immunology, Oral Roberts University, School of Medicine, Tulsa, OK 74137.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Line
Humans
Naegleria / pathogenicity*,  physiology
Tumor Cells, Cultured
Vero Cells
Virulence
Grant Support
ID/Acronym/Agency:
AI-18788-03/AI/NIAID NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The rehabilitation of patients with diabetes mellitus and ischemic heart disease
Next Document:  Protective immunity against Angiostrongylus cantonensis in rats following sensitizing infections.