Document Detail

Cytomorphologic features of immature ovarian teratoma in peritoneal effusion: a case report.
MedLine Citation:
PMID:  15945092     Owner:  NLM     Status:  MEDLINE    
We describe unusual cytologic features of the peritoneal fluid in a patient with immature ovarian teratoma. Immature embryonal and neuroectodermal components of such tumors are rarely observed in the ascites; to our knowledge, there have been only three reports of cytologic findings of immature teratoma cells in the ascites. Our patient was a 26-yr-old woman who presented with a huge pelvic mass. A grade 3 immature right ovarian teratoma was diagnosed pathologically. Cytologic examination of the ascitic fluid revealed a variety of neoplastic cells, including immature neuroepithelial cells forming rosette-like structures, keratinized squamous cells, squamoid metaplastic cells, and immature glial-appearing cells. Immunohistochemical analysis revealed that immature gastrointestinal elements and yolk sac elements were positive for alpha-fetoprotein. This is the first description of the cytologic features of non-neuroepithelial elements in the ascitic fluid in a patient with immature ovarian teratoma.
Katsuhide Ikeda; Genshu Tate; Takao Suzuki; Toshiyuki Mitsuya
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  33     ISSN:  8755-1039     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-06-15     Completed Date:  2005-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  39-42     Citation Subset:  IM    
Copyright Information:
2005 Wiley-Liss, Inc
Department of Pathology, Showa University Fujigaoka Hospital, Fujigaoka 1-30, Yokohama, Japan.
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MeSH Terms
Ascitic Fluid / chemistry,  pathology*
Intermediate Filament Proteins / analysis
Keratins / analysis
Neoplasm Staging
Ovarian Neoplasms / metabolism,  pathology*
Teratoma / metabolism,  pathology*
alpha-Fetoproteins / analysis
Reg. No./Substance:
0/Intermediate Filament Proteins; 0/KRT20 protein, human; 0/KRT7 protein, human; 0/Keratin-20; 0/Keratin-7; 0/alpha-Fetoproteins; 68238-35-7/Keratins

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