Document Detail

Cytomegalovirus retinitis: an unusual presentation as vitreous hemorrhage.
MedLine Citation:
PMID:  25372208     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: The purpose of this report is to describe an unusual presentation of vitreous hemorrhage (VH) in a patient with an immunosuppressive condition.
METHODS: Retrospective case report.
RESULTS: A 72-year-old woman with known T-cell prolymphocytic leukemia treated with a course of alemtuzumab presented to our department with a VH in her left eye after a fall. An initial diagnosis of hemorrhagic posterior vitreous detachment was made. However, as the VH was resolving, she was found to have underlying vitritis, occlusive vasculitis, and a pale optic nerve head. Vitreous biopsy confirmed cytomegalovirus retinitis. Despite treatment with intravenous foscarnet and oral valganciclovir, her vision continued to remain poor because of the severe damage from the retinal vasculitis and residual VH.
CONCLUSION: As indications for immunosuppression increase, the incidence of cytomegalovirus retinitis in non-HIV-immunosuppressed patients is expected to rise. Therefore, in this subgroup of patients, we should be aware of any underlying retinitis especially in cases with an unusual presentation of VH.
Soon Wai Ch'ng; Alexander Brent; Somnath Banerjee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  8     ISSN:  1937-1578     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2014  
Date Detail:
Created Date:  2014-11-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  50-1     Citation Subset:  IM    
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