| Cytomegalovirus-related congenital nephrotic syndrome with diffuse mesangial sclerosis. | |
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MedLine Citation:
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PMID: 16523262 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This case report describes congenital nephrotic syndrome in a 2-month-old girl associated with cytomegalovirus infection. Histological examination on renal biopsy showed diffuse mesangial sclerosis and cytomegalic inclusion bodies in the tubular cells and in some glomeruli. Cytomegalovirus (CMV) polymerase chain reaction (PCR) titer in serum was high. Remission of pulmonary and renal symptoms was achieved with ganciclovir in 3 weeks. No recurrence of proteinuria was observed during the follow-up period of 14 months. These finding suggested a causal relationship between congenital nephrotic syndrome and cytomegalovirus infection. |
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Authors:
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Nesrin Besbas; Umut Selda Bayrakci; Gulsev Kale; Ali Bulent Cengiz; Zuhal Akcoren; Devrim Akinci; Ilke Kilic; Aysin Bakkaloglu |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-03-08 |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 21 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-04-28 Completed Date: 2006-06-20 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 740-2 Citation Subset: IM |
Affiliation:
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Department of Pediatric Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiviral Agents / therapeutic use Cytomegalovirus Infections / complications*, diagnosis, drug therapy, transmission Female Ganciclovir / therapeutic use Glomerular Mesangium / pathology*, virology Humans Inclusion Bodies, Viral Infant Infectious Disease Transmission, Vertical Nephrotic Syndrome / congenital*, pathology, virology* Pregnancy Pregnancy Complications, Infectious Sclerosis |
| Chemical | |
Reg. No./Substance:
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0/Antiviral Agents; 82410-32-0/Ganciclovir |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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