Document Detail

Cytomegalovirus pneumonitis: spectrum of parenchymal CT findings with pathologic correlation in 21 AIDS patients.
MedLine Citation:
PMID:  8029414     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To identify characteristic features of cytomegalovirus (CMV) pneumonitis at computed tomography (CT), particularly markers that may help differentiate CMV from Pneumocystis carinii pneumonia. MATERIALS AND METHODS: Bronchoalveolar lavage (BAL) and biopsy results in 21 patients with acquired immunodeficiency syndrome, cytopathologic evidence of CMV infection without other infections, and available CT scans were retrospectively evaluated. CT findings were correlated with radiographic and pathologic findings when available. RESULTS: BAL findings were positive for CMV in only six cases, 13 patients had extrathoracic CMV infection, and 10 had Kaposi sarcoma. CT findings included ground-glass attenuation, dense consolidation, bronchial wall thickening or bronchiectasis, and interstitial reticulation without air-space disease (12 patients had discrete pulmonary nodules or masses). Biopsy revealed air-space disease as the dominant process in eight cases. Histopathologic findings correlated well with CT appearances. CONCLUSION: CMV pneumonitis should be suspected in patients with either extrathoracic CMV or documented Kaposi sarcoma, especially when radiographic or CT evidence of pulmonary nodules or masses exists.
G McGuinness; J V Scholes; S M Garay; B S Leitman; D I McCauley; D P Naidich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  192     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-08-11     Completed Date:  1994-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  451-9     Citation Subset:  AIM; IM; X    
Department of Radiology, New York University Medical Center/Tisch Hospital, NY 10016.
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MeSH Terms
AIDS-Related Opportunistic Infections / pathology,  radiography*
Cytomegalovirus Infections / pathology,  radiography*
Diagnosis, Differential
Lung / radiography
Middle Aged
Pneumonia, Pneumocystis / radiography
Pneumonia, Viral / pathology,  radiography*
Retrospective Studies
Tomography, X-Ray Computed*

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