Document Detail

Cytomegalovirus-induced thrombocytopenia and haemolysis in an immunocompetent adult.
MedLine Citation:
PMID:  8562398     Owner:  NLM     Status:  MEDLINE    
We describe a patient with severe symptomatic thrombocytopenia and haemolytic anaemia caused by cytomegalovirus (CMV) infection. As far as we know, this is the second case in the literature. Treatment with ganciclovir seemed to be more effective for thrombocytopenia than treatment with corticosteroids. The hypothetical mechanisms leading to thrombocytopenia and haemolysis in CMV infection are briefly discussed. In cases of acute thrombocytopenia and clinical manifestations of an infectious disease, with or without haemolysis, testing for CMV may be useful in connection with therapeutic consequences.
D J van Spronsen; W P Breed
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of haematology     Volume:  92     ISSN:  0007-1048     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-03-01     Completed Date:  1996-03-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  218-20     Citation Subset:  IM    
Department of Internal Medicine, Catharina Hospital, Eindhoven, The Netherlands.
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MeSH Terms
Acute Disease
Anemia, Hemolytic / drug therapy,  virology*
Cytomegalovirus Infections / complications*
Dexamethasone / therapeutic use
Drug Therapy, Combination
Ganciclovir / therapeutic use
Middle Aged
Thrombocytopenia / drug therapy,  virology*
Reg. No./Substance:
50-02-2/Dexamethasone; 82410-32-0/Ganciclovir
Comment In:
Br J Haematol. 1996 Nov;95(2):433-5   [PMID:  8904906 ]

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