Document Detail

Cytomegalovirus enterocolitis complicated by perforated appendicitis in a premature infant.
MedLine Citation:
PMID:  16863859     Owner:  NLM     Status:  MEDLINE    
A 9-week-old, former 30-week estimated gestational age premature infant had recurrent episodes of abdominal distention. Laparotomy revealed partial small bowel obstruction caused by ileocecal inflammation with stenosis, and a perforated appendix with fistulization into the cecum. The resected appendix and ileocecal junction showed intranuclear and intracytoplasmic viral inclusions, and were cytomegalovirus positive by immunoperoxidase staining, which implicated cytomegalovirus as the etiology of the recurring bouts of enterocolitis with appendicitis. Cytomegalovirus is frequently overlooked in the differential diagnosis of enterocolitis and chronic gastrointestinal symptoms in infants, but should be included as in older immunocompromised patients.
Nebbie Elizabeth Terry; Carol L Fowler
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  41     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-25     Completed Date:  2006-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1476-8     Citation Subset:  IM    
Memorial Health University Medical Center, Mercer University School of Medicine, Savannah Campus, Savannah, GA 31404, USA.
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MeSH Terms
Appendicitis / surgery,  virology*
Cytomegalovirus Infections / complications*
Diseases in Twins
Enterocolitis / virology*
Immunocompromised Host
Infant, Newborn
Infant, Premature / immunology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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