| Cytomegalovirus-associated acute hydramnios treated by amniocentesis and maternal indomethacin. | |
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MedLine Citation:
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PMID: 20021488 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 22-year-old pregnant woman noticed a rapid increase of abdominal growth, uterine tenderness and irregular contraction, for which she hospitalized at 25 weeks of gestation. An ultrasound examination demonstrated a single fetus with normal anatomy and massive hydramnios. Serial therapeutic amniocentesis was performed for relief of maternal symptoms and indomethacin compress was initiated. Both the maternal and amniotic fluid IgM were positive for cytomegalovirus (CMV). Maternal compress indomethacin was discontinued at 32 weeks. Cesarean section was performed due to fetal distress at 34 weeks of gestation. A female infant was delivered and the neonatal examination was within normal limits with urine culture positive for CMV. At 1 year of age the child was developing normally with normal hearing and no clinical sequelae of intrauterine CMV infection. We postulate that serial and large volume reduction of amniotic fluid by amniocentesis and compress indomethacin in our case interrupted the natural course and provided sufficient time for the fetus to recover from the acute phase of viral infection. |
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Authors:
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Nobuhiro Suzumori; Yukio Hattori; Saori Kaneko; Yoshikatsu Suzuki; Mayumi Sugiura-Ogasawara |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Congenital anomalies Volume: 49 ISSN: 1741-4520 ISO Abbreviation: Congenit Anom (Kyoto) Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-21 Completed Date: 2010-03-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306292 Medline TA: Congenit Anom (Kyoto) Country: Japan |
Other Details:
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Languages: eng Pagination: 274-5 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medicine, Nagoya, Japan. og.n.suz@med.nagoya-cu.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amniocentesis* Amniotic Fluid / virology* Cytomegalovirus Infections / congenital, drug therapy*, transmission Female Humans Indomethacin / therapeutic use* Infant, Newborn Infectious Disease Transmission, Vertical Polyhydramnios / therapy* Pregnancy Pregnancy Complications, Infectious / drug therapy*, virology Prenatal Diagnosis Ultrasonography, Prenatal Young Adult |
| Chemical | |
Reg. No./Substance:
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53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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