Document Detail

Cytomegalovirus Retinitis Following Intravitreal Triamcinolone Acetonide in a Patient with Chronic Uveitis on Systemic Immunosuppression.
MedLine Citation:
PMID:  23282087     Owner:  NLM     Status:  Publisher    
Abstract Purpose: To report a case of cytomegalovirus (CMV) retinitis in an HIV-negative, iatrogenically immunosuppressed patient with chronic uveitis following intravitreal triamcinolone acetonide (IVTA). Design: Observational case report. Methods: A 56-year-old female with chronic idiopathic panuveitis on azathioprine received a single 4-mg IVTA injection for macular edema and presented after 6 months with severe retinitis. Results: CMV was confirmed by polymerase chain reaction of vitreous fluid. The retinitis responded well to intravitreal ganciclovir, but she developed a rhegmatogenous retinal detachment and underwent vitrectomy with silicone oil tamponade. Conclusions: Sight-threatening CMV retinitis may develop in HIV-negative, immunosuppressed individuals after IVTA. Regular fundoscopy for up to 9 months after IVTA is recommended.
Anthony Grant Zaborowski
Related Documents :
23569427 - Clinical and virological characteristics of chronic hepatitis b patients with hepatic s...
23164297 - Outcome of anti-retroviral treatment in hiv-infected orphans and non-orphans at an art ...
24935567 - Hepatic steatosis: prevalence and host/viral risk factors in iranian patients with chro...
8217477 - Hiv-illness, social support, sense of coherence, and psychosocial well-being in a sampl...
16250867 - Thrombocytopenia in hiv disease: clinical relevance, physiopathology and management.
24900257 - Optimization of pharmacokinetics through manipulation of physicochemical properties in ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-2
Journal Detail:
Title:  Ocular immunology and inflammation     Volume:  -     ISSN:  1744-5078     ISO Abbreviation:  Ocul. Immunol. Inflamm.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312169     Medline TA:  Ocul Immunol Inflamm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Ophthalmology, Nelson R. Mandela School of Medicine , University of KwaZulu-Natal , Durban, South Africa.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Genetic variation in the 3' untranslated region of dengue virus serotype 3 strains isolated from mos...
Next Document:  25-gauge Vitrectomy for Complicated Chronic Endogenous/Autoimmune Uveitis: Predictors of Outcomes.