Document Detail

Cytology of urate milk in gouty arthritis: a case report.
MedLine Citation:
PMID:  17718129     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Synovial fluid (SF) analysis is a useful investigative procedure in the evaluation of various types of arthritides, including gouty arthritis. Rarely, gouty arthritis may present with effusion containing thick, milky white fluid. We report a case of gouty arthritis, describing cytologic features of the urate milk. CASE: A 42-year-old man presented with pain and swelling of multiple joints of long duration. Approximately 3 mL of milky white SF was obtained for white blood cell (WBC) count, with a clinical diagnosis of septic arthritis. Due to the gross nature of the sample, the WBC count could not be performed; however, cytologic examination of the sample revealed a massive amount of classic, needle-shaped urate crystals on routinely stained May-Grünwald-Giemsa smears, favoring a cytologic diagnosis of gouty arthritis. CONCLUSION: Gouty synovitis occasionally presents with thick, milky white urate-laden synovial effusions, which clinically may be mistaken for septic arthritis. This gross nature of the specimen may interfere with the performace of a WBC count on SF samples.
Neelaiah Siddaraju; Moatoshi Aier; Parasappa Joteppa Yaranal; Debdatta Basu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  51     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-08-27     Completed Date:  2007-09-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  586-8     Citation Subset:  IM    
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
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MeSH Terms
Ankle / pathology
Arthritis, Gouty / pathology*
Synovial Fluid / cytology*

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