| Cytology of columnar-cell variant of papillary thyroid carcinoma. | |
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MedLine Citation:
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PMID: 10787142 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Columnar cell variant of papillary carcinoma (CCV-PC) thyroid is a rare and aggressive tumor composed of tall columnar cells that form papillae, glands and solid structures. This paper describes fine needle aspiration (FNA) cytologic features in a case of CCV-PC occurring in the right thyroid lobe of a 27-year-old female. Smears showed tall columnar cells in monolayered, three-dimensional, acinar and occasional papillary clusters. Nuclei were oval or elongated and monomorphic. Nuclear pseudostratification, resembling that seen in respiratory epithelial cells, was present in some of the cell clusters. Occasional cells showed squamous or Hurthle cell metaplasia. Nuclear grooves and intranuclear cytoplasmic inclusions were not seen. Sections of the right lobectomy specimen showed an well-encapsulated CCV-PC with capsular and vascular permeation. Tall cell variant of papillary carcinoma (TCV-PC) can be distinguished from CCV-PC by the oxyphilia of the tumor cells and the absence of nuclear pseudostratification. Colorectal and endometrial adenocarcinomas metastatic to the thyroid may be difficult to distinguish from CCV-PC. |
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Authors:
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G Jayaram |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diagnostic cytopathology Volume: 22 ISSN: 8755-1039 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-05-31 Completed Date: 2000-05-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 227-9 Citation Subset: IM |
Affiliation:
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Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. GITA@medicine.med.um.edu.my |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy, Needle Carcinoma, Papillary / pathology*, surgery Female Humans Metaplasia Thyroid Neoplasms / pathology*, surgery Thyroidectomy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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