Document Detail

Cytological similarity between the heterochromatin of the large x and y chromosomes of the soft-furred field rat, Millardia meltada (family: muridae).
MedLine Citation:
PMID:  7273859     Owner:  NLM     Status:  MEDLINE    
Patterns of DNA replication, fluorescence, and meiotic pairing have been studied in the composite X and Y chromosomes of a rodent, the soft-furred field rat, Millardia meltada. The heterochromatin of both the chromosomes replicated during late S and fluoresces brightly with Netropsin-Olivomycin. The fluorescence with Actinomycin D-Hoechst is dull, suggesting that the heterochromatin of both the X and the Y is relatively GC-rich. When surface-spread testis cells are analyzed after silver staining considerable portions of the X and Y exhibit synapsis. On the basis of this study it appears that the heterochromatin of the X chromosome of M. meltada is substantially similar to that of the Y chromosome.
I Nanda; R Raman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  30     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1981  
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  77-82     Citation Subset:  IM    
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MeSH Terms
Chromosome Banding
DNA Replication
Heterochromatin / ultrastructure*
Muridae / genetics*
Sex Chromosomes / ultrastructure*
X Chromosome / ultrastructure*
Y Chromosome / ultrastructure*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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