Document Detail


Cytological effects of 60 Hz magnetic fields on human lymphocytes in vitro: sister-chromatid exchanges, cell kinetics and mitotic rate.
MedLine Citation:
PMID:  11255209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Incubation for 72 h of human peripheral blood cultures in the presence of 60 Hz sinusoidal magnetic fields (MF) at magnetic flux densities of 1.0, 1.5, and 2.0 mT led to stimulation of lymphocyte proliferation but had no influence on the frequency of sister-chromatid exchanges (SCE). The cytotoxic potential of MF combined with the mutagen Mitomycin-C also was analyzed. An opposite effect between MF exposure and Mitomycin-C treatment in terms of cell kinetics and mitotic rate was found, whereas no variation in SCE frequency was observed for this coexposure condition.
Authors:
J A Heredia-Rojas; A O Rodríguez-De La Fuente; M del Roble Velazco-Campos; C H Leal-Garza; L E Rodríguez-Flores; B de La Fuente-Cortez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bioelectromagnetics     Volume:  22     ISSN:  0197-8462     ISO Abbreviation:  Bioelectromagnetics     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-20     Completed Date:  2001-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008281     Medline TA:  Bioelectromagnetics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  145-9     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Wiley-Liss, Inc.
Affiliation:
Subdirección de Postgrado, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, México. jheredia@ccr.dsi.uanl.mx
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MeSH Terms
Descriptor/Qualifier:
Cell Division / drug effects,  radiation effects
Cell Survival / drug effects,  radiation effects
Cells, Cultured
Electromagnetic Fields*
Humans
Kinetics
Lymphocyte Activation / radiation effects
Lymphocytes / cytology,  drug effects,  radiation effects*
Mitomycin / pharmacology
Mitosis / drug effects,  radiation effects
Mitotic Index
Sister Chromatid Exchange / radiation effects*
Chemical
Reg. No./Substance:
50-07-7/Mitomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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