Document Detail


Cytological analyses of 14p+ variant by means of N-banding and combinations of silver staining and chromosome bandings.
MedLine Citation:
PMID:  85597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An inherited human karyological variant (14p+) has been studied with a number of cytochemical techniques. The short arm of this variant chromosome 14 is nearly as long as the long arm, giving the chromosome a submetacentric to metacentric appearance. In conventionally Giemsa-stained preparations, maximum of three secondary constrictions can be observed the marker arm. The secondary constrictions are silver-positive in Ag-NOR preparations. However, the entire arm stains deeply in N-banded preparations. The 14p+ arm is also Q-negative, C-negative, G-negative, and R-positive with an almost homogeneous texture. The difference between N-banding and silver staining is interpreted as the result of gene activities of the ribosomal cistrons.
Authors:
Y F Lau; W Wertelecki; R A Pfeiffer; F E Arrighi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Human genetics     Volume:  46     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1979-06-11     Completed Date:  1979-06-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  75-82     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Azure Stains
Cell Nucleolus
Chromosome Banding
Chromosomes, Human, 13-15 / ultrastructure*
Female
Genetic Variation
Humans
Silver
Staining and Labeling
Chemical
Reg. No./Substance:
0/Azure Stains; 7440-22-4/Silver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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