| CYTOLOGIC STUDIES ON RHEUMATIC FEVER : I. THE CHARACTERISTIC CELL OF THE RHEUMATIC GRANULOMA. | |
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MedLine Citation:
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PMID: 19870027 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Scrapings of subcutaneous nodules from ten patients with rheumatic fever were examined microscopically after being stained with supravital dyes. From the uniform results obtained, the following conclusions have been drawn. 1. Supravital staining of cells from these lesions gives information unobtainable with ordinary histologic methods. 2. The scrapings show a great predominance of certain cells almost entirely devoid of phagocytic power and not characterized by the reactions with neutral red which distinguish monocytes, epithelioid cells, and clasmatocytes. Hence they differ from the essential cells of the lesions of tuberculosis and experimental syphilis. These differences are probably of a functional and developmental rather than of a genetic nature. 3. The cells probably arise from the undifferentiated mesenchymal elements of loose connective tissue, although it is possible that endothelial cells take part in their formation in some instances. 4. Since there is little doubt that the subcutaneous rheumatic nodules are pathologically identical with rheumatic granulomata else-where in the body, these conclusions are considered applicable also to the Aschoff body cells of the myocardial submiliary nodules. |
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Authors:
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C McEwen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of experimental medicine Volume: 55 ISSN: 0022-1007 ISO Abbreviation: J. Exp. Med. Publication Date: 1932 Apr |
Date Detail:
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Created Date: 2010-06-23 Completed Date: 2010-06-23 Revised Date: 2010-09-28 |
Medline Journal Info:
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Nlm Unique ID: 2985109R Medline TA: J Exp Med Country: United States |
Other Details:
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Languages: eng Pagination: 745-59 Citation Subset: - |
Affiliation:
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Hospital of The Rockefeller Institute for Medical Research. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Exp Med ISSN: 0022-1007 ISSN: 1540-9538 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York Received Day: 11 Month: 1 Year: 1932 Print publication date: Day: 30 Month: 4 Year: 1932 Volume: 55 Issue: 5 First Page: 745 Last Page: 759 ID: 2132134 PubMed Id: 19870027 |
| CYTOLOGIC STUDIES ON RHEUMATIC FEVER : I. THE CHARACTERISTIC CELL OF THE RHEUMATIC GRANULOMA | |
| Currier McEwen | |
| From the Hospital of The Rockefeller Institute for Medical Research |
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