Document Detail

Cytologic patterns of reparative processes, true dysplasia and carcinoma of the gastric mucosa.
MedLine Citation:
PMID:  8091906     Owner:  NLM     Status:  MEDLINE    
The cytologic features of dysplasia and carcinoma of the stomach are still poorly defined. In a series of 90 cases, a precise correlation could be made between smears and histologic data. Cytology was sensitive enough to allow characterization of: (1) active repair/regeneration, associated, in a number of cases, with intestinal metaplasia (slight dysplasia); the cellular atypia is minimal; (2) true dysplasia (formerly moderate and severe); this preneoplastic state is characterized by cellular atypia within clusters; and (3) true carcinomas (intestinal or diffuse type); classic criteria for malignancy are present, with a prominent lack of cell cohesiveness, though distinction from dysplasia may be very difficult. The advantages of cytology are the survey of large mucosal areas, investigation of the cardial region, not always accessible to endoscopic biopsy, and exploration of large ulcers. With the adjunct of cytology, the specificity and sensitivity of endoscopy plus histology clearly increase.
J Hustin; G Lagneaux; M Donnay; J C Debongnie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  38     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1994 Sep-Oct
Date Detail:
Created Date:  1994-10-18     Completed Date:  1994-10-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  730-6     Citation Subset:  IM    
Department of Gastroenterology, Clinique St. Pierre, Ottignies, Belgium.
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MeSH Terms
Carcinoma, Signet Ring Cell / diagnosis,  pathology*
Gastric Mucosa / pathology*
Stomach Neoplasms / diagnosis,  pathology*

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