Document Detail

Cytologic features of peripheral squamous cell carcinoma of the lung.
MedLine Citation:
PMID:  7847010     Owner:  NLM     Status:  MEDLINE    
Cytologic features of 32 peripheral squamous cell carcinomas of the lung were reviewed. Fine needle aspiration biopsy and curettage showed most of the tumor cells to be arranged in irregular cell fragments consisting of relatively small cells with scanty cytoplasm. They possessed round to oval nuclei with coarsely granular chromatin, and some had large, prominent nucleoli. Keratinization was usually observed in small numbers of scattered cells, and a nuclear streaming arrangement was noted in some areas. When both keratinization and streaming arrangements were absent, correct subtyping was impossible (12 cases). These cytologic features were different from those of 31 hilar squamous cell carcinomas studied as controls; there many carcinoma cells showed keratinization, and small carcinoma cells were infrequent. However, in all cases, sputum cytology was correctly interpreted because squamous differentiation was easily recognized.
M Kamiya; Y Uei; Y Shimosato
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta cytologica     Volume:  39     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1995 Jan-Feb
Date Detail:
Created Date:  1995-03-06     Completed Date:  1995-03-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  61-8     Citation Subset:  IM    
Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenocarcinoma / pathology,  ultrastructure
Biopsy, Needle
Carcinoma / pathology,  ultrastructure
Carcinoma, Squamous Cell / pathology*,  ultrastructure
Cell Nucleus / ultrastructure
Chromatin / ultrastructure
Cytoplasm / ultrastructure
Diagnosis, Differential
Lung Neoplasms / pathology*,  ultrastructure
Sputum / cytology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Inaccuracy of cytologic diagnosis in high grade squamous intraepithelial lesions (CIN 3).
Next Document:  Cytologic characterization of bronchial epithelial changes in small cell carcinoma of the lung.